Two-photon calcium imaging of cross-orientation suppression across cortical depth in macaque V1. 4,785 ROIs across 28 depths (140-518um) reveal laminar shift from facilitation to suppression, paralleled by gradients in spatial frequency preference, tuning width, and orientation selectivity. Mixed-effects models and bootstrap CIs included.
python neuroscience calcium-imaging normalization visual-cortex macaque suite2p two-photon-imaging cross-orientation-suppression cortical-layers
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Feb 8, 2026 - Python